Is there Nicotine in CBD Liquid? There is no Nicotine in our CBD Liquid. It is possible to mix the liquid with nicotine-containing e-liquid. You then dilute both liquids so that the effect of the CBD as Nicotine will be less. Willy van Knippenberg February 04, 2019 00:51 Follow Have more questions? Submit a request 0 Comments Please sign in to leave a comment.