Is there Nicotine in CBD Liquid? There is no Nicotine in our CBD Liquid. It is possible to mix the liquid with nicotine-containing e-liquid. You then dilute both liquids so that the effect of the CBD as Nicotine will be less. Willy van Knippenberg November 30, 2017 15:40 Follow Have more questions? Submit a request 0 Comments Please sign in to leave a comment.